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Wake up america

the dual impact of insomnia means the effects don’t end when the
sun comes up–symptoms span both night & day. It’s time to prioritize both night & day, so you can help address
the entirety of the condition and maximize patient outcomes

73%

of people with insomnia symptoms reported a nighttime impairment2

data from a US general population study (N=1,003). Impairment defined as mild to very severe difficulty with sleep onset per item 1 of the Insomnia Severity Index (ISI).

show study details

a US general population cross-sectional study of 1,003 people aged 22-60 years; data include people with no clinically significant insomnia and people with mild to very severe symptoms per the ISI assessed using the Sleep, Health, Activity, Diet and Environment and Social Factors (SHADES) Survey.


patients experience nighttime impairments

based on the DSM-5, patients diagnosed with insomnia experience both nighttime & daytime impairments1

  • 38%

    reported difficulty initiating sleep at bedtime3

  • eye

    61%

    reported frequent or prolonged awakenings throughout the night3

  • sun

    52%

    reported awakening early in the morning with an inability to return to sleep3

data from a cross-sectional telephone survey of 6,791 people with insomnia assessed using the Brief Insomnia Questionnaire (BIQ). Patients met either DSM-IV-TR (primary insomnia), ICD-10 (non-organic insomnia), and/or RDC-ICSD-2 (insomnia disorder) criteria.

84%

of people with insomnia symptoms reported daytime impairment2

data from a US general population study (N=1,003).

show study details

a US general population cross-sectional study of 1,003 people aged 22-60 years; data include people with no clinically significant insomnia and people with mild to very severe symptoms per the ISI assessed using the Sleep, Health, Activity, Diet and Environment and Social Factors (SHADES) Survey.


patients experience daytime impairments

based on the DSM-5, patients diagnosed with insomnia experience both nighttime & daytime impairments2

  • day

    84%

    reported fatigue4

  • coffee

    71%

    reported low energy4

  • shoe

    91%

    reported interference with ability to function4

data from exploratory chart review from clinicians’ evaluation summaries, a self-report screening instrument, the Pittsburgh Sleep Quality Index, the Beck Depression Inventory, the Epworth Sleepiness Scale, and the Hopkins Symptom Checklist—90 in 94 patients with chronic insomnia. Values are obtained from the self-reported sleep questionnaire in the primary insomnia subgroup (n=45). Patients met DSM-IV criteria for primary insomnia.

this night & day

impact is felt by

many people

this night & day impact is felt

by many people

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9.5%

of people in the US have acute insomnia5*

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~20%

of these patients transition to chronic insomnia5*

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insomnia can occur in

people with or without

comorbidities1

insomnia can occur in people with or without comorbidities1

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22%

of women

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16%

of men

15-22%

of those aged 18‑54

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21-24%

of those aged ≥55

28-39%

of people in White, Black, Asian, and Hispanic communities report that their sleep needs are not being met

in the US, insomnia affects6:

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22%

of women

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16%

of men

15-22%

of those aged 18‑54

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21-24%

of those aged ≥55

insomnia spans ethnic & racial backgrounds7

28-39%

of people in White, Black, Asian, and Hispanic communities report that their sleep needs are not being met

*Estimates based on analysis of US community samples (N=2,861).

Age-adjusted prevalence of self-reported insomnia among US general population aged 18 years and older (N=34,509).

Study of US general population aged 25-60 years (N=1,007).

*Estimates based on analysis of US community samples (N=2,861).

Age-adjusted prevalence of self-reported insomnia among US general population aged 18 years and older (N=34,509).

Study of US general population aged 25-60 years (N=1,007).

the night & day

impact of

insomnia survey

the night & day impact of insomnia survey

to understand the hidden toll of insomnia, The Alliance for Sleep and Idorsia Pharmaceuticals conducted one of the largest US surveys among 300 primary care physicians (PCPs), 152 psychiatrists, and 1,001 US adults ages 18+ who have been diagnosed with insomnia by a healthcare provider or who have experienced difficulties sleeping for a period of time (ie, patient with sleep difficulties), of which8:

to understand the hidden toll of insomnia, The Alliance for Sleep and Idorsia Pharmaceuticals conducted one of the largest US surveys among 300 primary care physicians (PCPs), 152 psychiatrists, and 1,001 US adults ages 18+ who have been diagnosed with insomnia by a healthcare provider or who have experienced difficulties sleeping for a period of time (ie, patient with sleep difficulties), of which8:

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39%

of healthcare providers say that there are no good treatment choices; some current approaches have more risks than benefits

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41%

of patients are concerned about next day somnolence with prescription medications

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81%

of healthcare providers are worried about potential dependency or addiction to prescription medications

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patients continue to experience the dual impact of insomnia,
highlighting the need to talk about both night & day8,9

patients continue to experience the dual impact of insomnia,
highlighting the need to talk about both night & day8,9

it’s time to

address both

nights & days

it’s time to address

both nights & days

start the night & day

conversation with your

patients:

start the night & day conversation with your patients:

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expand the conversation
to include day

insomnia is about more than difficulty falling and staying asleep.1 Ask patients about daytime impairments, such as fatigue and headache, and their impact on school or work

proactively ask about
patients’ sleep

one study showed that only about 1/3 of patients tell their doctor they have trouble sleeping10

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revisit and discuss
management plans

some patients consistently face the dual impact of insomnia and may continue to struggle during the night & day8,9

American Academy of

Sleep Medicine (AASM)

Guidelines support

dual primary treatment goals11:

American Academy of Sleep Medicine (AASM) Guidelines support

dual primary treatment goals11:

improve sleep quality and quantity

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reduce daytime impairment

patients need a

management approach

that considers their nights

without ignoring their

days12,13

patients need a management approach that considers their nights

without ignoring their days12,13

About Idorsia Pharmaceuticals

Taking promising therapies from bench to bedside

Get to know us

Passion & curiosity for science to improve patients’ lives

Unlocking the power of innovation

Diversified pipeline

Targeting areas of high clinical unmet need

Questioning management standards

Not accepting the status quo in insomnia management

Idorsia is committed to providing support that gives patients easy and convenient access to our promising therapies

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