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reported daytime impairments in patients treated for insomnia
sleepiness
- fatigue
- tirednessa
- daytime sleepinessb
- somnolence
alertness/cognition
- dizziness
- disorientation
aOutcome recorded if text-based analysis of doctor notes returned at least 1 of the following keywords: exhausted, exhaustion, not rested, drained, depleted, worn out, worn-out, fatigue, fatigued, weary, lethargic.
bOutcome recorded if text-based analysis of doctor notes returned at least 1 of the following keywords: sleepy, sleepiness, sleep deprivation, excessive yawning, drowsy, drowsiness, dozy, doziness, difficulty staying awake, nap, napping, excessive daytime sleepiness (EDS).
Reference: Data on file, idorsia.
insomnia treatment classes
- benzodiazepines
- z-drugs
- melatonin receptor agonists
- dual orexin receptor antagonists (DORAs)
- histamine antagonists
- antidepressants
- other medications used to treat insomnia
approach to management
in addition to common trade-offs like risk of dependence and
next-day somnolence,* patients continue to experience unmet needs
in addition to common trade-offs like risk of dependence and
next-day somnolence,* patients continue to experience unmet needs
>50%
of patients have significant insomnia symptoms persist even while taking prescription sleep medication 6 days a week1†
~50%
of patients experience fatigue while being treated with some of the most commonly prescribed sleep medications2
†Adult patients aged ≥20 years diagnosed with insomnia by a clinician (N=193); patients with other sleep-wake disorders were excluded.
many primary care physicians struggle to find a sustainable management solution for their patients
The Alliance for Sleep and Idorsia Pharmaceuticals conducted one of the largest US surveys among 300 primary care physicians (PCPs), 152 psychiatrists, and 1,001 US adults ages 18+ who have been diagnosed with insomnia by a healthcare provider or who have experienced difficulties sleeping for a period of time (ie, patients with sleep difficulties), of which2:
39%
of healthcare providers say that there are no good treatment choices; some current approaches have more risks than benefits
41%
of patients are concerned about next-day somnolence with prescription medications
81%
of healthcare providers are worried about potential dependency or addiction to prescription medications
patients continue to experience the dual impact of insomnia, highlighting the need to talk about both night & day
